Compare
Tirzepatide vs Semaglutide
The facts side by side: what each compound is, how it is stored, what amounts research used, and what no one can tell you. This compares reference facts, it does not recommend one over another.
| Reference fact | Tirzepatide | Semaglutide |
|---|---|---|
| What it is | Tirzepatide is a lab-made peptide studied for how the body handles food and weight. It works on two body signals at once, called GIP and GLP-1 (a dual receptor agonist), instead of just one. | Semaglutide is a lab-made peptide. It is one of the most studied peptides for how the body handles food and weight. It works on a body signal called GLP-1 (a GLP-1 receptor agonist). |
| Category | Metabolic | Metabolic |
| Evidence | FDA-approved molecule | FDA-approved molecule |
| Common vial sizes | 5, 10, 15, 30, 60 mg | 3, 5, 10 mg |
| Amounts studied in research | 2.5 mg to 15 mg | 250 mcg to 2.4 mg |
| Shelf life once mixed | 42 days refrigerated | 56 days refrigerated |
| Storage note | Keep in the fridge, following your product's instructions. | Keep in the fridge, following your product's instructions. |
| What nobody knows | Approved as a medicine, so its approved product has official labeling. An unapproved research powder sold under the same name carries no assurance of identity, purity, or strength. | Approved as a medicine, so its approved product has official labeling. An unapproved research powder sold under the same name carries no assurance of identity, purity, or strength. |
Amounts studied are not recommendations
The “amounts studied” row reports the range that appears in research on each compound. It is context, not a suggested amount, and an amount studied in animals does not translate to a person. What no calculation can verify.